- Title
- Drop-out, adherence, and compliance in randomized controlled trials of exercise training in multiple sclerosis: Short report
- Creator
- Motl, Robert W; Russell, Daniel I; Pilutti, Lara A; Metse, Alexandra P; Marck, Claudia H; Chan, Bryan; Zheng, Peixuan; Learmonth, Yvonne C
- Relation
- Multiple Sclerosis Journal Vol. 30, Issue 4-5, p. 605-611
- Publisher Link
- http://dx.doi.org/10.1177/13524585241229332
- Publisher
- Sage
- Resource Type
- journal article
- Date
- 2024
- Description
- We documented reporting and rates of drop-out, adherence, and compliance from 40 randomized controlled trials (RCTs) included in our meta-analysis on safety of exercise training (ET) in MS. We adopted definitions and metrics of adherence and compliance provided by the MoXFo adherence group. Drop-out was reported in 100% of the RCTs and approximated 10% for intervention and control conditions. Adherence and compliance were reported in approximately 50% and 10% of the RCTs, respectively, and approximated 80% and 70%, respectively. Standardized metrics for reporting adherence and compliance are important in future RCTs for understanding the impact on outcomes and translation of research evidence into practice.
- Subject
- exercise; adherence; compliance; safety; rehabilitation
- Identifier
- http://hdl.handle.net/1959.13/1507947
- Identifier
- uon:56070
- Identifier
- ISSN:1352-4585
- Language
- eng
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